Murine tumor models are widely used in cancer research to study tumor biology, test new treatments, and evaluate potential drug candidates. These models involve the transplantation of tumor cells into mice, either subcutaneously or orthotopically, to mimic the human disease. The most common murine tumor models include xenografts and syngeneic models. Xenograft models involve the implantation of human tumor cells into immunocompromised mice, which lack the ability to reject foreign tissues. Syngeneic models, on the other hand, use mouse tumor cells transplanted into immunocompetent mice that can mount an immune response against the tumor. 

Our services encompass both xenograft tumor models, which involve the use of various immune-compromised mice either with or without human CD34+ hematopoietic stem cell or human PBMC reconstitution, as well as syngeneic tumor models.